Baneocin ointment, 20 g, Sandoz

Indications:
- Localized bacterial infections of the skin for example: boils, anthrax (only after surgical treatment), chin follicle, deep follicle, suppurative hydrosadenitis, periporitis, paronychia.
- Limited skin infections such as: contagious impetigo, infected leg ulcers, secondary infected eczema, secondarily infected wounds and cuts, hot water burns, other burns, post-surgery such as plastic and repair surgery, eg skin transplantation ( both prophylactically and in the form of ointment dressings).
- After major or minor surgery: can be used as an adjunct during postoperative care. Applying gauze pads on which Baneocin ointment has been applied may be helpful in patients with non-significant wounds (eg external ear canal infections, wounds, bedsores or surgical wounds left to heal per second).

Composition:
100 g ointment contains zinc bacitracin 25000 IU and neomycin 500000 IU in the form of neomycin sulfate and excipients: anhydrous lanolin, white Vaseline.

Method of administration:
The recommended dose for both adults and children is 2-3 applications Baneocin ointment per day.
In the case of a local treatment, it is recommended not to exceed the dose of 1 g neomycin per day (corresponding to 200 g of skin powder or Baneocin ointment) administered for a maximum period of 7 days. If treatment is repeated, this dose should be reduced by half.
The ointment is applied in a thin layer on the area to be treated; it can be covered with a bandage.

Contraindications:
Hypersensitivity to bacitracin, neomycin, other aminoglycoside antibiotics or to any of the excipients.
Extensive, severe skin damage (because absorption of the drug can cause ototoxicity with hearing loss).
Severe renal failure.
Pre-existing vestibular and / or cochlear lesions.
Application to the external auditory canal, in case of tympanic perforation. Applying to the breasts during breastfeeding.
Children under 2 years.

Warnings:
-In patients with hepatic and / or renal impairment, due to the increased risk of adverse reactions, tests of hepatic and renal function and audiometry are recommended before and during intensive treatment with Baneocin.
-In patients with chronic otitis media with long-term evolution, caution is required due to possible ototoxicity.
-In patients with acidosis, myasthenia gravis or other neuromuscular diseases, caution is required because, if uncontrolled absorption of the active substances in Baneocin occurs, neuromuscular blockade may occur. Calcium and neostigmine can be used to antagonize this blockade.
-Pregnancy and lactation:
Neomycin, like all aminoglycoside antibiotics, crosses the placenta. Lesions of the cochlear apparatus in the face have been described in the case of parenteral administration of high doses to the mother.
As systemic absorption of the active substances in Baneocin is possible, administration to pregnant or lactating women is not recommended, especially in topical breast applications.
-Effects on ability to drive and use machines Baneocin does not affect your ability to drive or use machines.

Precautions:
In case of prolonged use, the possibility of resistant micro-organisms, in particular fungi, should be considered. In these cases, if appropriate, appropriate treatment will be used.
In case of hypersensitivity reactions or superinfection, treatment should be discontinued.
The risk of hypersensitivity reactions is increased with prolonged use (over 8 days), use with chronic dermatitis, especially in stasis dermatitis, or use with occlusive dressings.

interactions
In case of systemic absorption, concomitant administration of cephalosporins or other aminoglycosides may potentiate nephrotoxicity.
Concomitant use of diuretics, such as ethacrynic acid or furosemide, may also aggravate oto- and nephrotoxicity. In patients receiving narcotics, anesthetics or muscle relaxants, Baneocin absorption may potentiate neuromuscular blockade.

Side effects:
In local applications on the skin and open lesions, Baneocin is generally well tolerated.
Prolonged treatment may cause hypersensitivity reactions such as erythema and dry skin, rash and pruritus.
It can also cause cross-hypersensitivity reactions.
Hypersensitivity reactions that manifest as contact eczema are extremely rare.
In case of prolonged use, resistant microorganisms can develop, especially fungi.
Patients with extensive skin lesions may experience systemic adverse reactions due to the absorption of active substances (eg vestibular and cochlear lesions, nephrotoxicity and neuromuscular blockade).
Overdose:
If the product is administered in larger quantities than recommended, nephro and ototoxicity may occur due to the absorption of the active substances.

Presentation:
20 g